The Complexity of Dynamics and Kinetics from Single Molecules to Cells

Steve Presse — spresse@asu.edu

Tamiki Komatsuzaki — tamiki@es.hokudai.ac.jp

Douglas Shepherd — Douglas.Shepherd@asu.edu

This workshop is dedicated to capturing structures and dynamic events from single molecules to cells, emphasizing biochemical labeling, optical approaches, and computational techniques. By bridging experimentalists and theorists from diverse fields, we aim to generate new paths forward for joint design and analysis of complex experiments.

Despite the wealth of experimental data, fundamental challenges common to all complex dynamical systems limit our ability to gain meaningful insight from processes. Such challenges include faithful labeling that does not alter the biology of interest, optical aberrations that limit imaging quality, low signal-to-noise due to fast image or low contrast labels, unwanted background, and other experimental realities. Paired with all of these issues are the ever-expanding dataset size and complexity, rapidly approaching petabytes across many dimensions, creating bottlenecks that limit our ability to extract quantitative information and further push our understanding of complex biological regulatory events.

The workshop intends to bring together scientists with an interest in unraveling more complete, multi-dimensional descriptions of biological systems with interest spanning novel optical methods to the role of AI in imaging and quantitative analysis.

We wish to ensure an intimate workshop setting, with no more than 20 to 25 participants. If you are interested in attending but have not received an invitation, please contact the workshop organizer before registering.

Sessions typically run mornings and late afternoons, leaving mid-day free for informal collaboration.

Travel to Telluride can be expensive; please assess your own potential travel costs before registering.

Please book your travel plans! The Montrose Regional Airport (MTJ) is the most reliable and convenient airport for Telluride.

Telluride Science can provide lodging starting as low as $215/night during off-peak weeks and as low as $250/night during peak-season at the Mountainside Inn. These affordable lodging options are limited and available first-come, first-serve. To encourage participants to secure affordable lodging, we offer a $100 discount on lodging provided through Telluride Science that is secured before the Early Bird deadline. Additionally, we work with many lodging providers in Telluride and Mountain Village to offer discounts between 10-15% off your total lodging balance. Additional information provided with registration.

If you have more questions about lodging, reach out to Sara at sara@telluridescience.org.

Registrations may be refunded less a $25 cancellation fee. If cancelled before the lodging cancellation deadline, lodging payments are refundable less a $100 cancellation fee. It is each participant's responsibility to confirm and understand their own lodging cancellation deadline. Travel insurance is highly recommended.