Coarse-Grained Modeling of Structure and Dynamics of Biomacromolecules

Andrzej Klockowski — Andrzej.Kloczkowski@nationwidechildrens.org

Robert Jernigan — jernigan@iastate.edu

The purpose of the workshop is to bring together eminent scholars with expertise in coarse-grained modeling to study the structure and dynamics of proteins, nucleic acids and other biological macromolecules. Several different aspects of coarse-grained modeling will be discussed, such as:

i) development of statistical coarse-grained potentials
ii) structure prediction based on coarse-grained modeling
iii) prediction of structural flexibility and low-frequency domain motions using normal mode analysis, elastic network models and computer simulations, and their importance for biological functions of macromolecules.

A special focus will be given to the analysis of conformational changes in biological systems using coarse-grained models and their applications to biomolecular machines. A significant emphasis will be given to the diversity at our workshop by having a good balance of gender, ethnic origin and U.S./Non-U.S. citizens among the invited speakers.

We wish to ensure an intimate workshop setting, with no more than 20 to 25 participants. If you are interested in attending but have not received an invitation, please contact the workshop organizer before registering.

Sessions typically run mornings and late afternoons, leaving mid-day free for informal collaboration.

Travel to Telluride can be expensive; please assess your own potential travel costs before registering.

Please book your travel plans! The Montrose Regional Airport (MTJ) is the most reliable and convenient airport for Telluride.

Telluride Science can provide lodging starting as low as $215/night during off-peak weeks and as low as $250/night during peak-season at the Mountainside Inn. These affordable lodging options are limited and available first-come, first-serve. To encourage participants to secure affordable lodging, we offer a $100 discount on lodging provided through Telluride Science that is secured before the Early Bird deadline. Additionally, we work with many lodging providers in Telluride and Mountain Village to offer discounts between 10-15% off your total lodging balance. Additional information provided with registration.

If you have more questions about lodging, reach out to Sara at sara@telluridescience.org.

Registrations may be refunded less a $25 cancellation fee. If cancelled before the lodging cancellation deadline, lodging payments are refundable less a $100 cancellation fee. It is each participant's responsibility to confirm and understand their own lodging cancellation deadline. Travel insurance is highly recommended.